The BIG FOUR of how we AGE

Sunday, May 5th, 2013

The Big Four

According to most researchers genetics account for only one-third of how we age; the other two-thirds are influenced by our expectations, choices and environment.    Improvements in public health and medicine have increased life expectancy.  Someone born in the USA in 2010 had a life expectancy of 78.2, and 70,000 Americans celebrated their 100th birthdays that year.  This is good news for the growing number who are redefining retirement and using their bonus years to do good work.  However, without good physical and mental health, living longer may not be a blessing, so it is important to live better, not just longer.   We can significantly improve how we age by focusing on what I call the “big four”-physical activity, social engagement, diet and nutrition, and life purpose.

Physical activity benefits our bodies in many ways:  improving strength and fitness, helping balance, improving mood, managing weight, and preventing or treating certain diseases.  But the benefits of physical activity don’t stop with our bodies; they extend to our brain function.  Numerous studies have shown that physical activity is one of the strongest factors in preventing or delaying Alzheimer’s and other forms of dementia.  A new study in the journal Neurology suggests that working out is more effective at protecting the brain than cognitive challenges such as games and puzzles.  According to the Mayo Clinic, people who are physically active are less likely to experience a decline in their mental function and have a lowered risk of developing Alzheimer’s disease.

Social connection could be the single most important factor in healthy aging.  One study of 7,000 men and women living in Alameda County, CA found that people who were not connected to others were three times as likely to die over the course of nine years as those who had strong social ties.  Those with social ties and unhealthful lifestyles actually lived longer than those with poor social ties but more health-promoting habits.  The Beta Blocker Heart Attack Trial of 2,300 men who had survived a heart attack found that those with strong social connections had only one-quarter the risk of death of those not socially connected, even when factors like smoking, diet, alcohol, exercise and weight were taken into account.

The Blue Zones study offers dramatic support for the importance of diet and nutrition to aging well.  The Blue Zones identified areas in the world that had the highest life expectancy or highest proportion of people living to 100 and looked at their common characteristics.  Of the nine shared characteristics, three dealt with diet and nutrition. Blue Zones’ inhabitants ate primarily plant-based diets with a heavy emphasis on beans.  They practiced the 80% rule of eating, stopping when they were no longer hungry and before they were full.  And, finally, all Blue Zones’ inhabitants except one drank alcohol moderately and regularly.

Living with purpose adds seven years to life expectancy according to the Blue Zones study.  Having a life purpose is what gets us out of bed in the morning and makes life worth living.  Richard Leider, life coach and author, defines the good life as “Living with the people you love, in the right place, doing good work on purpose.”  Purpose is where our talents and our passions intersect with a need.  It is meeting a need by doing what we love and do well, the intersection of our gifts, passions and values. Finding our encore career, where we can make a difference, can be a rich source of living with purpose.

Focusing on the “big four” and making even little changes can result in big rewards.

 

MUSIC and the BRAIN

Tuesday, April 16th, 2013

Music-BrainFor Daniel Levitin, music is not simply a distraction or a pastime, but a core element of our identity as a species.” We have a “musical brain,” he says, one of the big differences between us and the rest of the species with which we share the planet. Humans create music and art and they represent ideas. He believes those features were evolutionary adaptations.

Levitin is at Stanford precisely to teach that connection. His course (HumBio188) explores the evolutionary advantages that musicality might have conferred upon early human beings and the neurological underpinnings of musical experience.

He also is a lab scientist. His questions include: What is the brain doing when it hears music? What do we remember? What do we like? What do we expect? Setting lyrics aside, what makes a piece of music happy or sad or impossible to get out of your head?

http://www.stanford.edu/group/brainwaves/

 

Our Brains and Aging

Thursday, March 7th, 2013

Brains

Thanks to fMRI and some excellent research programs, we are learning more about the brain.  As we age, cognitive function seems to slow down and disorders like Alzheimer’s Disease, Diabetes, and Parkinson’s Disease all affect our memories.  Research into dementia is opening doors long closed.  Techniques of studying the brain are expanding rapidly.  In addition to knowing far more about genetics and the processes inside the nucleus of brain cells, we are more sure that diet, exercise, and active engaged involvement.  There are alternative solutions to drugs that prevent deterioration of our mental facilities, AND several research laboratories have now drugs in stages of Clinical Trials.

We are living longer, and the new knowledge encourages aging in place with dignity and independence!

 

The Righteous Mind and Jonathan Haidt

Thursday, August 30th, 2012

This book is a must read.  We make more decisions from intuition than we think, and we rationalize them with our intellect.  This has widespread implications for psychology, religion, and politics.   We can be “groupish” and individual simultaneously.  Haidt generates six different “foundations”.

 

His favoroite metaphor is a rider on an elephant.  The elephant represents our intuitions (outside of awareness, automatic actions) and the rider represents rational attempts to explain our actions.  The size difference matters!

 

 

MCI and Caffinated Coffee

Sunday, June 17th, 2012

My friend and colleague Alan Ivey sent this to those of us in the “Grindal group” studying the neurology and genetics of dimentia.

June 15, 2012 — Patients with mild cognitive impairment (MCI) may be able to avoid developing dementia by drinking several cups of coffee a day, the results of a new study suggest.

The study showed that patients with MCI who have a plasma caffeine level of 1200 ng/mL avoided progression to dementia over the following 2 to 4 years.

These patients exhibited a plasma cytokine profile that was exactly the same as that of Alzheimer’s disease (AD) transgenic mice that were given caffeinated coffee and didn’t progress to dementia. It’s therefore very likely that it’s caffeine from coffee, and not from other sources, that affords the cognitive protection, said study senior author Gary W. Arendash, PhD, research scientist, Bay Pines Veterans Affairs Hospital, St. Petersburg, Florida.

The research also suggests that certain cytokine patterns could signal for impending conversion to dementia among those with MCI, said Dr. Arendash.

The study is published in the June issue of the Journal of Alzheimer’s Disease

Executive Brain Functions

Wednesday, May 2nd, 2012

 

As we age, various aspects of normal aging, mild cognitive impairment,  and more serious diseases can lead to dimentia that  intrudes in the smooth way our brains use to work when we were younger.  A group of scientists coming from medicine and psychology meet monthly to learn what happens in the brain right down to cell nuncleii and epigenetic effects.  The more we learn, the more there is to learn!

 

 

 

 

Ctc Brain Health Meeting – Video Clip

Tuesday, March 13th, 2012

Linda Williams was the facilitator for the Ctc Brain Health Group on Feb. 22.

They took a video of one part of the meeting. Take a look at it and see how much fun these performers had….!

Brainhealth Meeting – Video Demonstration

Eight Intelligences!

Thursday, February 23rd, 2012

Linda Williams was our featured speaker at Brain Health.  The Educator/Coach introduced Howard Gardner’s Eight Intelligences and asked us which were our best.  We then worked in smaller groups to show the results! 

The eight intelligences are Linguistic (word smart), Logical (number smart), Interpersonal people smart), Intrapersonal (self smart), Musical (music smart), Visual/Spatial (picture smart), Naturalistic (nature smart) and Kinaesthetic (body smart).  To explore your own skills in each of these, go to this self test. You will see your profile in an advanced pie chart (Visual!).

Hoiw can we use this information to keep our brains in top shape for as long as possible?

At our next meeting in the last week of March, Dr. David Goodrich, one of the Group’s Leaders, will present on the “Executive Functions” of the Brain.  Watch for the announced location, date, and time.

 

Brain Transplants?

Thursday, February 23rd, 2012

The Future of Brain Transplants

  • By Peter Tyson
  • Posted 08.26.10
  • NOVA scienceNOW

Will we ever grow replacement brains or do whole-brain transplants?

 

Need a new body part? Tissue engineers are now growing human bladders, lungs, and other organs in the lab with the hope that, someday soon, such organs may replace diseased organs in people. Transplant surgeons, for their part, routinely place donated kidneys, hearts, and other organs into patients whose own organs are failing. They have transplanted hands, arms, even, famously, a face.

This has left me wondering, where does the brain come into all this? Will we someday grow replacement brains or do whole-brain transplants? Three questions leap to mind: Why would we? Could we? And should we?

A computer image of a brain being held in hands.On bad days, we may feel we’d like a brain transplant, but what are the prospects realistically? Some experts have actually put their minds to it.   Photo credit: © Henrik Jonsson/iStockphoto

 

I must admit to feeling a bit squeamish with the whole idea, which you might agree has a sizeable “yuck” factor. And I felt a little sheepish when I called experts to ask them about it. Would they dismiss me out of hand, beseeching me not to waste their time with a subject best left to science-fiction writers? But with science and medicine advancing at a dizzying pace, and with questionable medical procedures of the past as cautionary tales, it seemed like a subject worth addressing, if only perhaps to reject it as untenable, unconscionable, or simply too ghastly to contemplate.

Why would we?

First of all, why? What medical justification could exist for growing a new brain, or part of one, and placing it in someone whose own brain, or part of it, was removed?

Click here for the rest of this article

 

Early Alzheimer’s Symptoms

Friday, February 10th, 2012

From our good friend Allen Ivey:

Results showed that “yes” answers to the following AQ questions were significant indicators of aMCI:

• Does the patient repeat questions/statements in the same day?

• Does the patient have trouble remembering the date, year, and time?

• Does the patient have difficulty managing finances?

• Does the patient have a decreased sense of direction?

Items pertaining to repetition of statements, orientation, ability to manage finances, and visuospatial disorientation had high discriminatory power.

Self-Report Version in the Works

Additional analysis examining only these 4 AQ questions showed a sensitivity to aMCI of 80.30 and a specificity of 81.80. (Predictive power)

If you have a facility nearby that offers a “cognitive assessment”, and you or your parent are 60+, do it.  Early identification can mean everything.  New drugs are in  sages of clinical trials, and some offer much hope!